Cristina Fimiani

Cristina Fimiani

PhD student in Functional and Structural Genomics, IV year.

I got my Bachelor’s Degree in Molecular Biology at the University of Trieste in 2009, with a thesis focused on genetic factors involved in Multiple Sclerosis. As the study of the nervous system looked very interesting to me, I got the Master’s Degree in Neuroscience at the University of Trieste in 2012. I joined the Laboratory of Prof. Mallamaci since I became interested in the study of cerebral cortex development. My master’s thesis focused on developing an artificial ncRNA-based device to upregulate endogenous genes ad libitum.

I am currently working on RNA-based treatment of gene haploinsufficiencies. On one hand, I am trying to further optimize of our ncRNA-based artificial device to make it feasible for gene therapy. On the other hand I also aim to exploit small activating RNAs (miRNA-like) to stimulate gene transcription. I think that artificial manipulation of our genome and synthetic genomics are extremely exciting field, in particular applied to neurodevelopmental diseases.

Contact at SISSA