Simone Chiola

Simone Chiola

PhD student in Functional and Structural Genomics, II year

I graduated in Medical Biotechnology in 2014 at the University of Turin with a thesis based on molecular and transcriptional characterization of colorectal cancer patients. Now at SISSA I am involved in a project focused on the study of the transcriptional regulation of cerebral cortex development. In particular, taking advantage of genetically modified neurons, I am analyzing phenomena occurring upon misregulation of transcriptional factors (TFs) necessary to neuronal differentiation and architectural patterning. In parallel, I am carrying on an in vivo analysis on mice harboring similar genetic modifications and histological features. Studying the transcriptional landscape of neurons in cortex development is not just an exciting research experience for me, but also a unique possibility to dissect and characterize the fundamental mechanisms that regulate the behavior of a such fascinating and complex cell, the neuron.

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